Information You Need To Know!
Patient Resources
Recommended Reading
How To Achieve Healthy Aging by Neal Rozier MD
Bioidentical Hormone Replacement Therapy by Neal Rozier, MD (Monograph)
Avoiding Breast Cancer While Balancing Your Hormones by Joseph McWherter, MD, 2005
Articles
Summary of Major Published Studies
WOMEN’S HEALTH INITIATIVE STUDY (WHI)
*Used synthetic estrogen and progesterone (Prempro®) not natural hormones
*Average start age: 63 years
*Oral administration only
Increased Risks: Stroke (Up 41%), Heart Disease (Up 29%), Thrombosis (Up 111%), Breast CA (Up 26%)
Protective: Colon CA (Down 37%), Hip Fracture (Down 34%)
J. American Medical Association 2002; 288:321
WOMEN’S HEALTH INITIATIVE STUDY (WHI)
PREMARIN® ONLY (NO PROVERA®)
Increased Risk: Stroke(Up 39%), Thrombosis(Up 33%),
Protective:HeartDisease (Down9%), Breasts(Down23%), Colona(Down8%),Hip Fracture(Down39%)
J. American Medical Association 2004; 291:1701
FURTHER ANALYSIS OF THE WHI STUDY
For women on estrogen< 10 years since menopause there is a decreased coronary heart disease risk
For women on estrogen< 10 years since menopause there is a decreased mortality risk
*Conclusion: Estrogen may have a negative effect on damaged arteries but may have a positive effect on healthy vessels
J. American Medical Association 2007; 297:1465
RELATIVE RISKS OF BREAST CANCER
Genetic Mutation (BRCA 1/2) 10:1
Late age at first childbirth: 2:1
Benign breast disease: 1.5:1
Alcohol use: 1.4:1
Hormone replacement therapy: 1.3:1
RISK FOR BLOOD CLOTS, PHLEBITIS AND DEEP VEIN
THROMBOSIS WITH ORAL ESTROGEN
First Pass through the liver increases clotting factors (2.3/10,000 vs. 1.0/10,000 non-users)
*No increase in phlebitis and clot formation shown with transdermal preparations
J. American Medical Association 2004; 292:1581
Lancet 2003; 362:428
Circulation 2007; 115:840
DEMENTIA AND ALZHEIMER’S DISEASE STUDIES
WITH ESTROGEN USE
Cash County Memory Study: Estrogen use greater than 10 years reduced the risk of Alzheimer’s Disease to that of men of the same age (note that women have twice the incidence of Alzheimer’s disease compared with men)
J. American Medical Association 2002; 288:2123
WHIMS Study: Women who used any form of hormone therapy before the age of 65 were 50% less likely to develop Alzheimer’s disease or Dementia.
(Presented at the American Academy of Neurology Annual Meeting, May 2007)
SKIN CARE
Contents of D-More Perfect Collagen Serum
5% pharmaceutical grade collagen made fresh for very dry skin
Hyaluronic Acid
Collagen
Haberlea Rhodopensis Leaf Extract
Algae Extract
Mugwort Extract
Vitamin C
Plantago Lanceolata Leaf Extract
Aloe Vera
Contents of D-More Skin Whitening Cream
Evens out the skin tone
20% Vitamin C Ascorbate
Niacinamide
Perilla Frutescens Seed Oil
Vitamin E
Tricholoma Matsutake Extract
Licorice Extract
Advantages of The Collagenizer® with D-More Products
The Collagenizer® Flyer
COLLAGEN BIOLIFTING
Biolifting is a “soft skin rejuvenation” method that yields instant enhancement without needles and toxins and with no discomfort during or after treatment. Dermoelectroporation® technology utilizes the skin’s water based intercellular channels to promote transdermal delivery of cosmeceuticals by a continuous very low reversed polarity current. The Collagenizer® features proprietary technology that is substantially different from electrophoresis, microcurrent galavanic devices – and it delivers an instant and long lasting effect.
For cosmetic application,efficacy and sensation are the important criteria. From the standpoint of patient comfort, the less irritation the product causes, the more acceptable it is.
Dermoelectroporation® - the No-Needle Collagen treatment
Dermoelectroporation is a patented technology developed in Florence, Italy, by Mattioli Engineering and clinically researched and tested at Siena University. Clinical trials have demonstrated the possibility to obtain, for the first time ever, transdermal delivery of large molecules like collagen.
Advantages of Dermoelectroporation®
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No variation in the skin’s pH.
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Non-invasive action. No trauma from injections
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Instant visible enhancement
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No tissue or cell damage at all
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No discomfort, no downtime, no bruising
The COLLAGENIZER® is providing a continuous reversed polarity current, despite the fact that the average current is zero. Moreover large molecules, like collagen, are transdermally delivered for the first time ever.
The absence of temporary pH change allows for the use of traditional scrubs like microdermabrasion before treatment. Clinical studies at the University of Florence, Italy, have proven that microdermabrasion pre-treatment enhances the transdermal delivery with no adverse effects.